Potential mechanisms of Zika‐linked microcephaly

نویسندگان

  • Emily Merfeld
  • Lily Ben-Avi
  • Mason Kennon
  • Kara L Cerveny
چکیده

A recent outbreak of Zika virus (ZIKV) in Brazil is associated with microcephaly in infants born of infected mothers. As this pandemic spreads, rapid scientific investigation is shedding new light on how prenatal infection with ZIKV causes microcephaly. In this analysis we provide an overview of both microcephaly and ZIKV, explore the connection between prenatal ZIKV infection and microcephaly, and highlight recent insights into how prenatal ZIKV infection depletes the pool of neural progenitors in the developing brain. WIREs Dev Biol 2017, 6:e273. doi: 10.1002/wdev.273 For further resources related to this article, please visit the WIREs website.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2017